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Generated: September 17, 2019

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Patent: 8,507,505

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Summary for Patent: 8,507,505
Title:Dihydropyrazolopyrimidinone derivative
Abstract: The present invention relates to a compound of General Formula (I) below, among others. In the Formula, Ar.sup.1 is an optionally substituted aryl or heteroaryl group; R.sup.1 is a hydrogen atom, an optionally substituted C1-C6 alkyl group, or an optionally substituted aryl, aralkyl, or heteroaryl group; R.sup.2 is an optionally substituted aryl, aralkyl, or heteroaryl group; and R.sup.3 is a hydrogen atom or a C1-C6 alkyl group. A compound of the present invention has an excellent Wee1 kinase inhibiting effect, and is therefore useful in the filed of medicine, particularly in various types of cancer therapy. ##STR00001##
Inventor(s): Bamba; Makoto (Ibaraki, JP), Furuyama; Hidetomo (Kanagawa, JP), Sakamoto; Toshihiro (Ibaraki, JP), Sunami; Satoshi (Ibaraki, JP), Takahashi; Keiji (Chiba, JP), Yamamoto; Fuyuki (Ibaraki, JP), Yoshizumi; Takashi (Ibaraki, JP)
Assignee: MSD K.K. (Chiyoda-Ku, Tokyo, JP)
Application Number:13/133,673
Patent Claims:see list of patent claims

Details for Patent 8,507,505

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck ELSPAR asparaginase VIAL 101063 001 1978-01-10 ➤ Sign Up MSD K.K. (Chiyoda-Ku, Tokyo, JP) 2028-12-12 RX search
Chiron PROLEUKIN aldesleukin VIAL 103293 001 1992-05-05 ➤ Sign Up MSD K.K. (Chiyoda-Ku, Tokyo, JP) 2028-12-12 RX search
Genentech RITUXAN rituximab VIAL 103705 001 1997-11-26 ➤ Sign Up MSD K.K. (Chiyoda-Ku, Tokyo, JP) 2028-12-12 RX search
Eisai Inc ONTAK denileukin diftitox VIAL 103767 001 1999-02-05 ➤ Sign Up MSD K.K. (Chiyoda-Ku, Tokyo, JP) 2028-12-12 RX Orphan search
Genentech HERCEPTIN trastuzumab VIAL; INTRAVENOUS 103792 001 1998-09-25 ➤ Sign Up MSD K.K. (Chiyoda-Ku, Tokyo, JP) 2028-12-12 RX Orphan search
Genzyme CAMPATH alemtuzumab VIAL; INTRAVENOUS 103948 001 2001-05-07 ➤ Sign Up MSD K.K. (Chiyoda-Ku, Tokyo, JP) 2028-12-12 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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