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Generated: July 23, 2019

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Patent: 8,501,423

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Summary for Patent: 8,501,423
Title:Measuring circulating therapeutic antibody, antigen and antigen/antibody complexes using ELISA assays
Abstract: The present invention relates to the field of immunology and hyperproliferative diseases. More specifically, the present invention relates to a method of detecting and monitoring therapeutic antibody:antigen complex, soluble antigen and soluble therapeutic antibody, wherein a patient has undergone at least one course of immunotherapy. Yet further, levels of therapeutic antibody:antigen complexes, soluble antigens or soluble therapeutic antibodies may be measured and used to stage or monitor a hyperproliferative disease.
Inventor(s): Albitar; Maher (Sugar Land, TX), Keating; Michael J. (Houston, TX), Manshouri; Taghi (Houston, TX)
Assignee: Board of Regents, The University of Texas System (Austin, TX)
Application Number:13/543,560
Patent Claims:see list of patent claims

Details for Patent 8,501,423

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source
Genzyme LEMTRADA alemtuzumab INJECTABLE;INJECTION 103948 003 2001-05-07 ➤ Sign Up Board of Regents, The University of Texas System (Austin, TX) ➤ Sign Up RX Orphan search
Genzyme CAMPATH alemtuzumab VIAL; INTRAVENOUS 103948 002 2001-05-07 ➤ Sign Up Board of Regents, The University of Texas System (Austin, TX) ➤ Sign Up RX Orphan search
Genzyme CAMPATH alemtuzumab VIAL; INTRAVENOUS 103948 001 2001-05-07 ➤ Sign Up Board of Regents, The University of Texas System (Austin, TX) ➤ Sign Up RX Orphan search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source

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International Patent Family for US Patent 8,501,423

Country Patent Number Publication Date
World Intellectual Property Organization (WIPO) 03024993 Mar 27, 2003
World Intellectual Property Organization (WIPO) 03024993 Oct 16, 2003
United States of America 10018638 Jul 10, 2018
United States of America 2003068664 Apr 10, 2003
United States of America 2010221761 Sep 02, 2010
United States of America 2011236994 Sep 29, 2011
United States of America 2012107846 May 03, 2012
Country Patent Number Publication Date

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