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Generated: September 23, 2019

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Patent: 8,486,957

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Summary for Patent: 8,486,957
Title:Chemotherapeutic for inducing an MSH2-dependent apoptotic pathway
Abstract: A method of treating cancer in a subject in need thereof comprises administering said subject reserpine, yohimbine, an analog thereof, or a pharmaceutically acceptable salt or prodrug thereof, in an amount effective to treat the cancer. Compounds and compositions useful for carrying out the method are also described.
Inventor(s): Salsbury, Jr.; Freddie R. (Winston-Salem, NC), Scarpinato; Karin D. (Clemmons, NC), King; S. Bruce (Walnut Cove, NC)
Assignee: Wake Forest University Health Sciences (Winston-Salem, NC)
Application Number:12/711,306
Patent Claims:see list of patent claims

Details for Patent 8,486,957

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck ELSPAR asparaginase VIAL 101063 001 1978-01-10 ➤ Sign Up Wake Forest University Health Sciences (Winston-Salem, NC) 2028-08-22 RX search
Genentech RITUXAN rituximab VIAL 103705 001 1997-11-26 ➤ Sign Up Wake Forest University Health Sciences (Winston-Salem, NC) 2028-08-22 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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