Patent: 8,486,957

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Summary for Patent: 8,486,957

Title:	Chemotherapeutic for inducing an MSH2-dependent apoptotic pathway
Abstract:	A method of treating cancer in a subject in need thereof comprises administering said subject reserpine, yohimbine, an analog thereof, or a pharmaceutically acceptable salt or prodrug thereof, in an amount effective to treat the cancer. Compounds and compositions useful for carrying out the method are also described.
Inventor(s):	Salsbury, Jr.; Freddie R. (Winston-Salem, NC), Scarpinato; Karin D. (Clemmons, NC), King; S. Bruce (Walnut Cove, NC)
Assignee:	Wake Forest University Health Sciences (Winston-Salem, NC)
Application Number:	12/711,306
Patent Claims:	see list of patent claims

Details for Patent 8,486,957

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Recordati Rare Diseases, Inc.	ELSPAR	asparaginase	For Injection	101063	01/10/1978	⤷ Try a Trial	2027-08-24
Genentech, Inc.	RITUXAN	rituximab	Injection	103705	11/26/1997	⤷ Try a Trial	2027-08-24
Idec Pharmaceuticals Corp.	RITUXAN	rituximab	Injection	103737	02/19/2002	⤷ Try a Trial	2027-08-24
Genentech, Inc.	RITUXAN HYCELA	rituximab and hyaluronidase human	Injection	761064	06/22/2017	⤷ Try a Trial	2027-08-24
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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