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Last Updated: September 30, 2020

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Patent: 8,460,860

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Summary for Patent: 8,460,860
Title:Cancellous bone treated with collagenase and essentially free of blood cells
Abstract: A bone implant comprising cancellous bone that is essentially free of blood cells, and which has been treated with at least a loosening agent, such as collagenase and/or a digestive enzyme, for a time and at a concentration to loosen the osteogenic cells in the cancellous bone matrix. The osteogenic cells in the matrix are viable cells. The treatment of the cancellous bone with at least one loosening agent enables the osteogenic cells to be more available for carrying our their osteogenic function and to provide for an increased rate of bone formation.
Inventor(s): Williams; Michelle LeRoux (Laurel, MD), Mills; Charles Randal (Finksburg, MD), Monroy; Rodney (Aberdeen, MD)
Assignee: NuVasive, Inc. (San Diego, CA)
Application Number:11/799,606
Patent Claims:see list of patent claims

Details for Patent 8,460,860

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04   Start Trial NuVasive, Inc. (San Diego, CA) 2026-05-08 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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