Get our Free Patent Expiration Newsletter

Serving hundreds of leading biopharmaceutical companies globally:

Healthtrust
Argus Health
Moodys
Teva
Harvard Business School
Cipla

Generated: July 23, 2019

DrugPatentWatch Database Preview

Patent: 8,445,486

Try a free trialSee Plans and Pricing

« Back to Dashboard

Summary for Patent: 8,445,486
Title:Triazine compounds as PI3 kinase and mTOR inhibitors
Abstract: Compounds of formula I ##STR00001## wherein: R.sup.1 is ##STR00002## and R.sup.2, R.sup.4, and R.sup.6-9 are defined herein, and pharmaceutically acceptable salts and esters thereof. These compounds inhibit PI3 kinase and mTOR, and may be used to treat diseases mediated by PI3 kinase and mTOR, such as a variety of cancers. Methods for making and using the compounds of this invention are disclosed. Various compositions containing the compounds of this invention are also disclosed.
Inventor(s): Venkatesan; Aranapakam Mudumbai (Rego Park, NY), Chen; Zecheng (New City, NY), Dehnhardt; Christoph Martin (New York, NY), Dos Santos; Osvaldo (Astoria, NY), Delos Santos; Efren Guillermo (Nanuet, NY), Zask; Arie (New York, NY), Verheijen; Jeroen Cunera (Highland Mills, NY), Kaplan; Joshua Aaron (Nyack, NY), Richard; David James (Warwick, NY), Ayral-Kaloustian; Semiramis (Tarrytown, NY), Mansour; Tarek Suhayl (New City, NY), Gopalsamy; Ariamala (Mahwah, NJ), Curran; Kevin Joseph (Congers, NY), Shi; Mengxiao (Eastchester, NY)
Assignee: Wyeth LLC (Madison, NJ)
Application Number:13/490,309
Patent Claims:see list of patent claims

Details for Patent 8,445,486

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source
Novartis Pharms EXTAVIA interferon beta-1b INJECTABLE; SUBCUTANEOUS 125290 001 2009-08-14 ➤ Sign Up Wyeth LLC (Madison, NJ) ➤ Sign Up RX search
Biogen Idec TYSABRI natalizumab VIAL; SINGLE-USE 125104 001 2004-11-23 ➤ Sign Up Wyeth LLC (Madison, NJ) ➤ Sign Up RX search
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 002 2004-02-26 ➤ Sign Up Wyeth LLC (Madison, NJ) ➤ Sign Up RX search
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 001 2004-02-26 ➤ Sign Up Wyeth LLC (Madison, NJ) ➤ Sign Up RX search
Serono Inc REBIF interferon beta-1a SYRINGE 103780 002 2002-03-07 ➤ Sign Up Wyeth LLC (Madison, NJ) ➤ Sign Up RX search
Serono Inc REBIF interferon beta-1a SYRINGE 103780 001 2002-03-07 ➤ Sign Up Wyeth LLC (Madison, NJ) ➤ Sign Up RX search
Biogen AVONEX interferon beta-1a VIAL 103628 001 1996-05-17 ➤ Sign Up Wyeth LLC (Madison, NJ) ➤ Sign Up RX search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source

Subscribe to access the full database, or try a Free Trial

International Patent Family for US Patent 8,445,486

Country Patent Number Publication Date
South Africa 201007204 Dec 28, 2011
World Intellectual Property Organization (WIPO) 2009143313 Nov 26, 2009
World Intellectual Property Organization (WIPO) 2009143317 Nov 26, 2009
United States of America 10022381 Jul 17, 2018
United States of America 2009291079 Nov 26, 2009
United States of America 2009304692 Dec 10, 2009
United States of America 2011312955 Dec 22, 2011
Country Patent Number Publication Date

Subscribe to access the full database, or try a Free Trial

Make Better Decisions: Try a trial or see plans & pricing

Serving hundreds of leading biopharmaceutical companies globally:

Fuji
QuintilesIMS
UBS
US Army
Healthtrust
Cipla

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.