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Last Updated: December 5, 2020

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Patent: 8,435,951

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Summary for Patent: 8,435,951
Title:Treating neoplasms with neurotoxin
Abstract: The present invention provides a method of treating a cancer using a neurotoxin, preferably Botulinum toxin (\"BTX\"). The application of a neurotoxin around a cancer acts to decrease the contractile forces of the muscles surrounding a neoplasm which normally squeeze cancer cells through efferent channels leaving the cancer vicinity to distant sites. Also, the application of the toxin at sites distant from the cancer enhances cellular and humoral immunologic functions which further contributes to cancer cell death and spread. Following administration of botulinum toxin around and distant to a cancer, it is noticed that local, regional, and distant spread is reduced or eliminated. Immunomodulation with botulinum toxin is also valuable in treating other disease that may or may not be associated with cancers, such as viral-induced growths, viral conditions, fungal disease, chronic wounds, graft versus host disease, autoimmune disease, and HIV.
Inventor(s): Shaari; Christopher (Demarest, NJ)
Assignee: Toxcure, Inc. (Demarest, NJ)
Application Number:12/725,955
Patent Claims:see list of patent claims

Details for Patent 8,435,951

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Elan Pharm MYOBLOC botulinum toxin type b VIAL 103846 001 2000-12-08   Start Trial Toxcure, Inc. (Demarest, NJ) 2024-09-23 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

International Patent Family for US Patent 8,435,951

Country Patent Number Estimated Expiration
World Intellectual Property Organization (WIPO) 2006034404   Start Trial
World Intellectual Property Organization (WIPO) 2010062955   Start Trial
World Intellectual Property Organization (WIPO) 2011066316   Start Trial
United States of America 2009028972   Start Trial
United States of America 2010172939   Start Trial
>Country >Patent Number >Estimated Expiration

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Serving leading biopharmaceutical companies globally:

Boehringer Ingelheim
Express Scripts
Johnson and Johnson

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