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Last Updated: January 26, 2021

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Patent: 8,435,752

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Summary for Patent: 8,435,752
Title:Gene polymorphisms predictive for dual TKI therapy
Abstract: The invention provides compositions and methods for determining the likelihood of successful treatment with dual therapy such as lapatinib. The methods comprise determining the genomic polymorphism or expression level of a gene present in a predetermined region of a gene of interest and correlating the polymorphism or expression level to the predictive response. Patients identified as likely responsive are then treated with the appropriate therapy.
Inventor(s): Lenz; Heinz-Josef (Los Angeles, CA)
Assignee: University of Southern California (Los Angeles, CA)
Application Number:12/523,514
Patent Claims:see list of patent claims

Details for Patent 8,435,752

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech Inc HERCEPTIN HYLECTA trastuzumab; hyaluronidase-oysk INJECTABLE;SUBCUTANEOUS 761106 001 2019-02-28   Start Trial University of Southern California (Los Angeles, CA) 2027-01-18 RX search
Genentech HERCEPTIN trastuzumab VIAL; INTRAVENOUS 103792 001 1998-09-25   Start Trial University of Southern California (Los Angeles, CA) 2027-01-18 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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