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Last Updated: October 1, 2020

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Patent: 8,420,792

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Summary for Patent: 8,420,792
Title:Suppressor tRNA transcription in vertebrate cells
Abstract: This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in vertebrate cells. The components include orthogonal tRNA\'s, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNA\'s/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in vertebrate cells are also provided.
Inventor(s): Tian; Feng (San Diego, CA), Norman; Thea (San Diego, CA), Chu; Stephanie (San Diego, CA)
Assignee: Ambrx, Inc. (La Jolla, CA)
Application Number:12/440,013
Patent Claims:see list of patent claims

Details for Patent 8,420,792

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Baxter Hlthcare Corp MYXREDLIN insulin human SOLUTION;INTRAVENOUS 208157 001 2019-06-20   Start Trial Ambrx, Inc. (La Jolla, CA) 2026-09-08 RX search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 004 2015-01-23   Start Trial Ambrx, Inc. (La Jolla, CA) 2026-09-08 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 003 2015-01-23   Start Trial Ambrx, Inc. (La Jolla, CA) 2026-09-08 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 002 2015-01-23   Start Trial Ambrx, Inc. (La Jolla, CA) 2026-09-08 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 001 2015-01-23   Start Trial Ambrx, Inc. (La Jolla, CA) 2026-09-08 RX Orphan search
Microbix Biosystems KINLYTIC urokinase INJECTABLE;INJECTION 021846 003 1978-01-16   Start Trial Ambrx, Inc. (La Jolla, CA) 2026-09-08 DISCN search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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