Patent: 8,415,382

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Summary for Patent: 8,415,382

Title:	Substituted benzazoles and methods of their use as inhibitors of RAF Kinase
Abstract:	New substituted benzazole compounds, compositions and methods of inhibition of Raf kinase activity in a human or animal subject are provided. The new compounds compositions may be used either alone or in combination with at least one additional agent for the treatment of a Raf kinase mediated disorder, such as cancer.
Inventor(s):	Costales; Abran (El Cerrito, CA), Hansen; Teresa (Danville, CA), Levine; Barry H. (Lafayette, CA), McBride; Christopher (Oakland, CA), Poon; Daniel J. (Oakland, CA), Ramurthy; Savithri (Walnut Creek, CA), Renhowe; Paul A. (Danville, CA), Shafer; Cynthia M. (El Sobrante, CA), Subramanian; Sharadha (San Ramon, CA), Verhagen; Joelle (Richmond, CA)
Assignee:	Novartis Vaccines and Diagnostics, Inc. (Emeryville, CA)
Application Number:	12/205,028
Patent Claims:	see list of patent claims

Details for Patent 8,415,382

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Number	Approval Date	Patent No.	Assignee	Patent Expiration	Status	Orphan	Source
Genentech	HERCEPTIN	trastuzumab	VIAL; INTRAVENOUS	103792	001	1998-09-25	➤ Try a Free Trial	Novartis Vaccines and Diagnostics, Inc. (Emeryville, CA)	➤ Try a Free Trial	RX	Orphan	search
Genentech	RITUXAN	rituximab	VIAL	103705	001	1997-11-26	➤ Try a Free Trial	Novartis Vaccines and Diagnostics, Inc. (Emeryville, CA)	➤ Try a Free Trial	RX		search
Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Number	Approval Date	Patent No.	Assignee	Patent Expiration	Status	Orphan	Source

International Patent Family for US Patent 8,415,382

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Country	Patent Number	Publication Date
World Intellectual Property Organization (WIPO)	2005037273	Apr 28, 2005
United States of America	2005192287	Sep 01, 2005
United States of America	2009035309	Feb 05, 2009
United States of America	2013224195	Aug 29, 2013
United States of America	7423150	Sep 09, 2008
Taiwan	200526208	Aug 16, 2005
Country	Patent Number	Publication Date

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