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Generated: September 24, 2019

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Patent: 8,394,924

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Summary for Patent: 8,394,924
Title:Directed engagement of activating Fc receptors
Abstract: The present invention features engineered proteins that include a first polypeptide that specifically binds a first target (e.g., a cellular target, such as a cell-surface antigen) and a second polypeptide that selectively binds an activating FcR.
Inventor(s): Wittrup; K. Dane (Chestnut Hill, MA), Howland; Shanshan Wu (Singapore, SG)
Assignee: Massachusetts Institute of Technology (Cambridge, MA)
Application Number:12/605,273
Patent Claims:see list of patent claims

Details for Patent 8,394,924

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Centocor Inc REOPRO abciximab INJECTABLE; INJECTION 103575 001 1994-12-22   Try a Free Trial Massachusetts Institute of Technology (Cambridge, MA) 2028-10-23 RX search
Genentech RITUXAN rituximab VIAL 103705 001 1997-11-26   Try a Free Trial Massachusetts Institute of Technology (Cambridge, MA) 2028-10-23 RX search
Novartis SIMULECT basiliximab VIAL; SINGLE-USE 103764 001 1998-05-12   Try a Free Trial Massachusetts Institute of Technology (Cambridge, MA) 2028-10-23 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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