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Last Updated: August 4, 2020

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Patent: 8,394,398

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Summary for Patent: 8,394,398
Title:Methods of administering rapamycin analogs with anti-inflammatories using medical devices
Abstract: A medical device comprising a supporting structure capable of including or supporting a pharmaceutically acceptable carrier or excipient, which carrier or excipient may include one or more therapeutic agents or substances, with the carrier including a coating on the surface thereof, and the coating including the therapeutic substances, such as, for example, drugs. Supporting structures for the medical devices that are suitable for use in this invention include, but are not limited to, coronary stents, peripheral stents, catheters, arterio-venous grafts, by-pass grafts, and drug delivery balloons used in the vasculature. Drugs that are suitable for use in this invention include, but are not limited to, ##STR00001## This drug can be used in combination with another drug including those selected from anti-proliferative agents, anti-platelet agents, anti-inflammatory agents, anti-thrombotic agents, cytotoxic drugs, agents that inhibit cytokine or chemokine binding, cell de-differentiation inhibitors, anti-lipaedemic agents, matrix metalloproteinase inhibitors, cytostatic drugs, or combinations of these drugs.
Inventor(s): Toner; John L. (Libertyville, IL), Burke; Sandra E. (Libertyville, IL), Cromack; Keith R. (Gurnee, IL), Mack; Matthew (Chicago, IL)
Assignee: Abbott Laboratories (Abbott Park, IL)
Application Number:11/548,827
Patent Claims:see list of patent claims

Details for Patent 8,394,398

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Abbvie Inc HUMIRA adalimumab VIAL 125057 002 2002-12-31   Start Trial Abbott Laboratories (Abbott Park, IL) 2017-09-26 RX search
Abbvie Inc HUMIRA adalimumab SYRINGE 125057 001 2002-12-31   Start Trial Abbott Laboratories (Abbott Park, IL) 2017-09-26 RX search
Ekr Therap RETAVASE reteplase VIAL 103786 001 1998-05-06   Start Trial Abbott Laboratories (Abbott Park, IL) 2017-09-26 RX search
Centocor Inc REOPRO abciximab INJECTABLE; INJECTION 103575 001 1994-12-22   Start Trial Abbott Laboratories (Abbott Park, IL) 2017-09-26 RX search
Genentech CATHFLO ACTIVASE alteplase VIAL 103172 003 1987-11-13   Start Trial Abbott Laboratories (Abbott Park, IL) 2017-09-26 RX search
Genentech ACTIVASE alteplase VIAL; SINGLE-USE 103172 002 1987-11-13   Start Trial Abbott Laboratories (Abbott Park, IL) 2017-09-26 RX search
Genentech ACTIVASE alteplase VIAL; SINGLE-USE 103172 001 1987-11-13   Start Trial Abbott Laboratories (Abbott Park, IL) 2017-09-26 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

International Patent Family for US Patent 8,394,398

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