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Last Updated: October 1, 2020

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Patent: 8,372,861

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Summary for Patent: 8,372,861
Title:Inhibitors of the unfolded protein response and methods for their use
Abstract: Compounds that are inhibitors of the unfolded protein response and endonuclease IRE1 are provided, together with compositions comprising such compounds, and methods for their use in the treatment of various disorders, such as cancer, autoimmune disorders, and diabetes. Also provided are packaged pharmaceuticals comprising these compositions. The compositions may be administered in combination with another therapeutic agent.
Inventor(s): Koong; Albert C. (Los Altos, CA), Feldman; Douglas E. (Mountain View, CA)
Assignee: The Board of Trustees of the Leland Stanford Junior University (Palo Alto, CA)
Application Number:12/280,793
Patent Claims:see list of patent claims

Details for Patent 8,372,861

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 002 2004-02-26   Start Trial The Board of Trustees of the Leland Stanford Junior University (Palo Alto, CA) 2026-02-27 RX Orphan search
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 001 2004-02-26   Start Trial The Board of Trustees of the Leland Stanford Junior University (Palo Alto, CA) 2026-02-27 RX Orphan search
Imclone ERBITUX cetuximab VIAL; INTRAVENOUS 125084 001 2004-06-18   Start Trial The Board of Trustees of the Leland Stanford Junior University (Palo Alto, CA) 2026-02-27 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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Boehringer Ingelheim
Baxter
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