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Last Updated: September 30, 2020

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Patent: 8,367,069

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Summary for Patent: 8,367,069
Title:Cytotoxic T cell defined EGFR peptide and an optimized derivative peptide
Abstract: The invention provides a polypeptide having a sequence of amino acids consisting of IXDFGLAKL (SEQ ID NO: 1), as well as a nucleic acid encoding the polypeptide, vector comprising the nucleic acid, cell comprising the vector, and compositions thereof. The invention also provides a method of inducing a T-cell response in a patient with epithelial cancer, and a method inhibiting epithelial cancer, wherein the methods comprise administering the composition of the invention. The invention further provides a method of stimulating a cell with the inventive polypeptide and a cell so stimulated.
Inventor(s): Ferris; Robert L. (Pittsburgh, PA), Andrade; Pedro (Pittsburgh, PA), Lopez-Albaitero; Andres (Pittsburgh, PA)
Assignee: University of Pittsburgh--of the Commonwealth System of Higher Education (Pittsburgh, PA)
Application Number:12/959,073
Patent Claims:see list of patent claims

Details for Patent 8,367,069

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Imclone ERBITUX cetuximab VIAL; INTRAVENOUS 125084 001 2004-06-18   Start Trial University of Pittsburgh--of the Commonwealth System of Higher Education (Pittsburgh, PA) 2028-06-02 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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Serving leading biopharmaceutical companies globally:

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