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Last Updated: December 5, 2021

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Patent: 8,361,536

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Summary for Patent: 8,361,536
Title:Method for fixing antibody on the surface of medical instrument
Abstract: A method for fixing antibody on the surface of medical instrument, mainly includes: 1) pre-treating the instrument surface; 2) preparing holes: preparing multicrystal phase structure which has same size holes in the surface of the instrument by chemical corrosion, electrochemical corrosion, anodic oxidation, micro-arc oxidation, micro-arc nitridation; 3) post-treating the instrument surface; 4) fixing the antibody: immerging the bare metal scaffold which has holes in surface into a buffer solution containing antibody, adjusting the pH value of the antibody buffer solution, fixing the antibody on the surface of the instrument by the attraction between positive and negative charge and hole effect; and 5) confirming the effectiveness of the fixed antibody by artificial simulation hemodynamics and detecting method of antibody activity in scaffold surface.
Inventor(s): Yu; Zhanjiang (Beijing, CN)
Assignee: Lepu Medical Technology (Beijing) Co., Ltd. (Beijing, CN)
Application Number:12/593,110
Patent Claims:see list of patent claims

Details for Patent 8,361,536

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Janssen Biotech, Inc. REOPRO abciximab Injection 103575 1994-12-22 ⤷  Try it Free 2027-05-23
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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