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Generated: July 22, 2019

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Patent: 8,343,929

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Summary for Patent: 8,343,929
Title:Treating neoplasms with neurotoxin
Abstract: The present invention provides a method of treating a neoplasm using a neurotoxin, preferably botulinum toxin. Neurotoxin administered around a neoplasm acts to decrease the contractile forces of the muscles surrounding a neoplasm which normally squeeze neoplastic cells through efferent channels leaving the neoplasm to distant sites. The present invention also provides a method of administering botulinum toxin at sites distant from the neoplasm, thereby enhancing cellular and humoral immunologic functions, which further contribute to neoplastic cell death. Following administration of botulinum toxin around or distant to a neoplasm as described herein, local, regional, and distant spread of neoplastic cells is reduced or eliminated. Immunomodulation with botulinum toxin is also valuable in treating other diseases that may or may not be associated with cancers, such as viral-induced growths, viral conditions, fungal disease, chronic wounds, graft versus host disease, autoimmune disease, and HIV.
Inventor(s): Shaari; Christopher (Demarest, NJ)
Assignee: Toxcure, Inc. (Demarest, NJ)
Application Number:12/592,540
Patent Claims:see list of patent claims

Details for Patent 8,343,929

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source
Elan Pharm MYOBLOC botulinum toxin type b VIAL 103846 001 2000-12-08 ➤ Try a Free Trial Toxcure, Inc. (Demarest, NJ) ➤ Try a Free Trial RX search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source

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International Patent Family for US Patent 8,343,929

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Serving hundreds of leading biopharmaceutical companies globally:

McKinsey
Colorcon
Fuji
AstraZeneca
Queensland Health
Express Scripts

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