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Last Updated: September 27, 2020

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Patent: 8,323,270

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Summary for Patent: 8,323,270
Title:Enhanced method for delivering bevacizumab (avastin) into a brain tumor using an implanted magnetic breather pump
Abstract: A magnetically controlled pump is implanted into the brain of a patient and delivers a plurality of medicating agents mixed with Avastin at a controlled rate corresponding to the specific needs of the patient. The current invention comprises a flexible double walled pouch that is formed from two layers of polymer. The pouch is alternately expanded and contracting by magnetic solenoid. When contracted, the medicating agent Avastin is pushed out of the pouch through a plurality of needles. When the pouch is expanded, surrounding cerebral fluid is drawn into the space between the double walls of the pouch from which it is drawn through a catheter to an analyzer. In cases where a tumor resection is not performed, an intratumoral catheter will be implanted. Cerebral fluid drawn from the patient is analyzed. The operation of the apparatus and hence the treatment is remotely controlled based on these measurements and displayed through an external controller.
Inventor(s): Shachar; Yehoshua (Santa Monica, CA), Chen; Thomas C. (La Canada, CA), Farkas; Leslie (Ojai, CA), Marx; Bruce (Ojai, CA), Johnson; David (West Hollywood, CA), Farkas; Laszlo (Ojai, CA)
Assignee: Pharmaco-Kinesis Corporation (Inglewood, CA)
Application Number:12/581,770
Patent Claims:see list of patent claims

Details for Patent 8,323,270

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 001 2004-02-26   Start Trial Pharmaco-Kinesis Corporation (Inglewood, CA) 2039-02-26 RX Orphan search
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 002 2004-02-26   Start Trial Pharmaco-Kinesis Corporation (Inglewood, CA) 2039-02-26 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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