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Last Updated: September 20, 2020

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Patent: 8,318,674

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Summary for Patent: 8,318,674
Title:Local treatment of bone defects
Abstract: A method of local treatment of specific bone defects such as osteoporosis or bone cysts comprises the step of local administration of a formulation comprising a fusion peptide containing a first domain comprising PTH or BMP 2 or BMP 7, and a second domain comprising a covalently crosslinkable substrate domain; and a material suitable of forming a biodegradable matrix suitable for cellular growth or in-growth, wherein the fusion peptide is covalently linked to the matrix. In one embodiment, the matrix contains one or more contrast agents, and is preferably formed in the absence of a growth factor. The matrix may be used in the treatment of fluid-filled cysts such as Tarlov cysts, ovarian cysts, arachnoid cysts, aneurysmal bone cysts or hepatic cysts.
Inventor(s): Schense; Jason (Zurich, CH), Watson; John (Zumikon, CH), Arrighi; Isabelle (Zurich, CH)
Assignee: Kuros Biosurgery AG (Zurich, CH)
Application Number:11/326,924
Patent Claims:see list of patent claims

Details for Patent 8,318,674

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Bayer Hlthcare TRASYLOL aprotinin INJECTABLE;INJECTION 020304 001 1994-02-07   Start Trial Kuros Biosurgery AG (Zurich, CH) 2025-01-06 DISCN search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 001 2015-01-23   Start Trial Kuros Biosurgery AG (Zurich, CH) 2025-01-06 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 002 2015-01-23   Start Trial Kuros Biosurgery AG (Zurich, CH) 2025-01-06 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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Baxter
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AstraZeneca

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