Make Better Decisions - Finding and Evaluating Generic and Branded Drug Market Entry Opportunities

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Generated: August 22, 2019

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Patent: 8,304,425

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Summary for Patent: 8,304,425
Title:Pyrrolidinone, pyrrolidine-2,5-dione, pyrrolidine and thiosuccinimide derivatives, compositions and methods for treatment of cancer
Abstract: The present invention relates to pyrrolidin-2-one, pyrrolidin-2,5-dione, pyrrolidine and thiosucciniroide compounds of formulae (I)-(IV), and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising pyrrolidin-2-one, pyrrolidin-2,5-dione, pyrrolidine and thiosuccinimide compounds. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a compound of pyrrolidin-2-one, pyrrolidin-2,5-dione, pyrrolidine and thiosuccinimide compound of the present invention. ##STR00001##
Inventor(s): Wang; Jianqiang (Acton, MA), Ali; Syed M. (North Andover, MA), Kelleher; Eugene (Wellesley, MA), Liu; Yanbin (Acton, MA), Hill; Jason (Auburndale, MA), Ashwell; Mark A. (Carlisle, MA)
Assignee: ArQule, Inc. (Woburn, MA)
Application Number:12/664,550
Patent Claims:see list of patent claims

Details for Patent 8,304,425

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech HERCEPTIN trastuzumab VIAL; INTRAVENOUS 103792 001 1998-09-25 ➤ Sign Up ArQule, Inc. (Woburn, MA) 2027-06-22 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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