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Patent: 8,299,106
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Summary for Patent: 8,299,106
| Title: | Compositions of kinase inhibitors and their use for treatment of cancer and other diseases related to kinases |
| Abstract: | The present invention relates to novel thiazole-substituted indolin-2-ones as inhibitors of CSCPK and related kinases; to methods of inhibiting cancer stem cells by using a kinase inhibitor; to pharmaceutical compositions containing such compounds; and to methods of using such compounds in the treatment of a protein kinase related disorder in a mammal; and to processes of making such compounds and intermediates thereof. |
| Inventor(s): | Li; Chiang Jia (Cambridge, MA), Liu; Ji-Feng (Winchester, MA), Li; Youzhi (Westwood, MA), Li; Wei (Wayland, MA), Rogoff; Harry (Wrentham, MA) |
| Assignee: | Boston Biomedical, Inc. (Norwood, MA) |
| Application Number: | 12/676,869 |
| Patent Claims: | see list of patent claims |
Details for Patent 8,299,106
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Number | Approval Date | Patent No. | Assignee | Estimated Patent Expiration | Status | Orphan | Source |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Genentech Inc | HERCEPTIN HYLECTA | trastuzumab; hyaluronidase-oysk | INJECTABLE;SUBCUTANEOUS | 761106 | 001 | 2019-02-28 | Start Trial | Boston Biomedical, Inc. (Norwood, MA) | 2027-09-06 | RX | search | |
| Genentech | AVASTIN | bevacizumab | VIAL; INTRAVENOUS | 125085 | 002 | 2004-02-26 | Start Trial | Boston Biomedical, Inc. (Norwood, MA) | 2027-09-06 | RX | Orphan | search |
| Genentech | AVASTIN | bevacizumab | VIAL; INTRAVENOUS | 125085 | 001 | 2004-02-26 | Start Trial | Boston Biomedical, Inc. (Norwood, MA) | 2027-09-06 | RX | Orphan | search |
| Imclone | ERBITUX | cetuximab | VIAL; INTRAVENOUS | 125084 | 001 | 2004-06-18 | Start Trial | Boston Biomedical, Inc. (Norwood, MA) | 2027-09-06 | RX | Orphan | search |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Number | >Approval Date | >Patent No. | >Assignee | >Estimated Patent Expiration | >Status | >Orphan | >Source |
International Patent Family for US Patent 8,299,106
| Country | Patent Number | Publication Date |
|---|---|---|
| World Intellectual Property Organization (WIPO) | 2009033033 | Apr 30, 2009 |
| World Intellectual Property Organization (WIPO) | 2009033033 | Mar 12, 2009 |
| United States of America | 2010285006 | Nov 11, 2010 |
| United States of America | 2012321622 | Dec 20, 2012 |
| >Country | >Patent Number | >Publication Date |
