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Last Updated: September 27, 2020

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Patent: 8,293,240

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Summary for Patent: 8,293,240
Title:Method of treating drug-resistant cancer
Abstract: Systems and methods for treating inflammatory and proliferative diseases, and wounds, using as a pharmacon a UCP and/or Fas antibody or other inhibitor, or combination thereof, and a therapeutically acceptable amount of a fatty acid metabolism inhibitor and/or a therapeutically acceptable amount of a glucose metabolism inhibitor, optionally in combination with one or more chemotherpeutic agents. In preferred embodiments, the invention combines an antibody against UCP and/or Fas antigen with an oxirane carboxylic acid, represented by etomoxir, and/or with a 2-deoxyglucose compound, represented by 2-deoxy-D-glucose. The systems and methods of the invention can be used to treat drug-resistant or multi-drug resistant cancers.
Inventor(s): Newell; Martha Karen (Colorado Springs, CO), Newell; Evan (Menlo Park, CA), Villalobos-Menuey; Elizabeth (Monument, CO)
Assignee: The Regents of the University of Colorado (Denver, CO)
Application Number:12/390,753
Patent Claims:see list of patent claims

Details for Patent 8,293,240

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech HERCEPTIN trastuzumab VIAL; INTRAVENOUS 103792 001 1998-09-25   Start Trial The Regents of the University of Colorado (Denver, CO) 2024-01-08 RX Orphan search
Genentech Inc HERCEPTIN HYLECTA trastuzumab; hyaluronidase-oysk INJECTABLE;SUBCUTANEOUS 761106 001 2019-02-28   Start Trial The Regents of the University of Colorado (Denver, CO) 2024-01-08 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

International Patent Family for US Patent 8,293,240

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