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Last Updated: October 1, 2020

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Patent: 8,277,440

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Summary for Patent: 8,277,440
Title:Implantable device for controlled, extended delivery of parathyroid hormone
Abstract: Method and devices are provided for extended and controlled delivery of parathyroid hormone to a patient. The method includes implanting a medical device into the patient, the medical device comprising a substrate, a plurality of reservoirs in the substrate, a release system contained in each of the reservoirs, wherein the release system comprises parathyroid hormone; and controllably releasing a pharmaceutically effective amount of the parathyroid hormone from the reservoirs. The parathyroid hormone can be released intermittently, such as once daily over an extended period (e.g., two months, ten months, or more.). The device can further include reservoirs containing a bone resorption inhibitor or other drug for release. The devices are useful in delivering PTH for the treatment and prevention of bone loss, such as associated with osteoporosis.
Inventor(s): Ausiello; Dennis (Wellesley Hill, MA), Santini, Jr.; John T. (North Chelmsford, MA), Herman; Stephen J. (Andover, MA), Prescott; James H. (Cambridge, MA), Uhland; Scott A. (Medford, MA), Maloney; John M. (Cambridge, MA), Polito; Benjamin F. (Lebanon, NH)
Assignee: MicroCHIPS, Inc. (Waltham, MA)
Application Number:12/358,850
Patent Claims:see list of patent claims

Details for Patent 8,277,440

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 004 2015-01-23   Start Trial MicroCHIPS, Inc. (Waltham, MA) 2022-09-04 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 003 2015-01-23   Start Trial MicroCHIPS, Inc. (Waltham, MA) 2022-09-04 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 002 2015-01-23   Start Trial MicroCHIPS, Inc. (Waltham, MA) 2022-09-04 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 001 2015-01-23   Start Trial MicroCHIPS, Inc. (Waltham, MA) 2022-09-04 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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