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Generated: September 24, 2019

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Patent: 8,273,768

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Summary for Patent: 8,273,768
Title:Iso CA-4 and analogues thereof as potent cytotoxic agents inhibiting tubuline polymerization
Abstract: The invention relates to a compound of the formula (I) in which: R.sub.1, R.sub.2 and R.sub.3 are independently a methoxy group optionally substituted by one or more fluorine atoms; R.sub.4 is a hydrogen atom; R.sub.5 and R.sub.6 are identical and each represent a hydrogen or fluorine atom; A is a cycle selected from the group including aryl and heteroaryl groups, wherein said groups can be substituted.
Inventor(s): Alami; Mouad (Bussy Saint Georges, FR), Brion; Jean-Daniel (Saint Leu la Foret, FR), Provot; Olivier (Sartrouville, FR), Peyrat; Jean-Francois (Villebon sur Yvette, FR), Messaoudi; Samir (Palaiseau, FR), Hamze; Abdallah (Bourg la Reine, FR), Giraud; Anne (Le Perreux sur Marne, FR), Bignon; Jerome (Le Val Saint Germain, FR), Bakala; Joanna (Paris, FR), Liu; Jian-Miao (Paris, FR)
Assignee: Centre National de la Recherche Scientifique (CNRS) (Paris, FR)
Application Number:12/594,495
Patent Claims:see list of patent claims

Details for Patent 8,273,768

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck ELSPAR asparaginase VIAL 101063 001 1978-01-10   Try a Free Trial Centre National de la Recherche Scientifique (CNRS) (Paris, FR) 2027-04-04 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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