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Generated: August 19, 2019

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Patent: 8,273,534

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Summary for Patent: 8,273,534
Title:Predictors of patient response to treatment with EGF receptor inhibitors
Abstract: The present invention provides methods and compositions to facilitate determining whether an EGFR-expressing cancer in an individual is an EGFR inhibitor-responsive cancer, as well as methods for determining the likelihood that a patient having an EGFR-expressing cancer will exhibit a beneficial response to an EGFR inhibitor therapy. The methods generally involve determining a normalized expression level of a gene product that correlates with EGFR inhibitor responsiveness.
Inventor(s): Baker; Joffre B. (Montara, CA), Watson; Drew (Los Altos, CA), Maddala; Tara (Redwood City, CA), Shak; Steven (Hillsborough, CA), Mauro; David J. (Redwood City, CA), Ford; Shirin K. (Redwood City, CA)
Assignee: Genomic Health, Inc. (Redwood City, CA) Bristol-Myers Squibb Company (Princeton, NJ)
Application Number:12/465,503
Patent Claims:see list of patent claims

Details for Patent 8,273,534

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Imclone ERBITUX cetuximab VIAL; INTRAVENOUS 125084 001 2004-06-18   Try a Free Trial Genomic Health, Inc. (Redwood City, CA) Bristol-Myers Squibb Company (Princeton, NJ) 2028-05-14 RX Orphan search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source

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