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Last Updated: December 7, 2021

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Patent: 8,241,848

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Summary for Patent: 8,241,848
Title:Distinguishing PCA3 messenger RNA species in benign and malignant prostate tissues
Abstract: This invention concerns the discovery of two distinct PCA3 mRNA sequences. One of these sequences corresponds to a short PCA3 mRNA molecule whereas the other PCA3 RNA molecule is longer as it comprises an additional sequence between exon 3 and exon 4a. The short RNA is associated with prostate cancer whereas the long RNA sequence is associated with a non-malignant state of the prostate. Based on the differential expression levels of these two PCA3 RNA sequences, protocols for the diagnosis of prostate disease are provided. The invention also relates to therapeutic approaches to prostate cancer.
Inventor(s): Busse; Ursula (Saint-Louis, FR), Chypre; Camille (Annecy, FR), Fradet; Yves (Quebec, CA)
Assignee: DiagnoCure Inc. (Quebec, Quebec, CA)
Application Number:13/080,262
Patent Claims:see list of patent claims

Details for Patent 8,241,848

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 1986-06-04 ⤷  Try it Free 2019-09-29
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 ⤷  Try it Free 2019-09-29
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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