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Last Updated: September 24, 2020

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Patent: 8,217,227

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Summary for Patent: 8,217,227
Title:Recombinant DNA constructs and methods for controlling gene expression
Abstract: The present invention provides molecular constructs and methods for use thereof, including constructs including heterologous miRNA recognition sites, constructs for gene suppression including a gene suppression element embedded within an intron flanked on one or on both sides by non-protein-coding sequence, constructs containing engineered miRNA or miRNA precursors, and constructs for suppression of production of mature microRNA in a cell. Also provided are transgenic plant cells, plants, and seeds containing such constructs, and methods for their use. The invention further provides transgenic plant cells, plants, and seeds containing recombinant DNA for the ligand-controlled expression of a target sequence, which may be endogenous or exogenous. Also disclosed are novel miRNAs and miRNA precursors from crop plants including maize and soy.
Inventor(s): Allen; Edwards (O\'Fallon, MO), Gilbertson; Larry A. (Chesterfield, MO), Huang; Shihshieh (Woodland, CA), Malvar; Thomas (North Stonington, CT), Roberts; James K. (Chesterfield, MO)
Assignee: Monsanto Technology LLC (St. Louis, MO)
Application Number:11/545,072
Patent Claims:see list of patent claims

Details for Patent 8,217,227

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04   Start Trial Monsanto Technology LLC (St. Louis, MO) 2039-02-26 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04   Start Trial Monsanto Technology LLC (St. Louis, MO) 2039-02-26 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04   Start Trial Monsanto Technology LLC (St. Louis, MO) 2039-02-26 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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