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Last Updated: December 5, 2019

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Patent: 8,216,571

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Summary for Patent: 8,216,571
Title:Fully human anti-VEGF antibodies and methods of using
Abstract: Disclosed herein are fully human antibodies and antigen-binding fragments thereof that specifically bind human VEGF and inhibit VEGF binding to VEGF-R1 and VEGF-R2, and therefore inhibit VEGF signaling. The antibodies and antigen-binding fragments disclosed herein may be used, for example, to treat angiogenesis and conditions associated with angiogenesis both in vivo and in vitro.
Inventor(s): Ramachandra; Sumant (Northbrook, IL), Bishop; Walter Robert (Pompton Plains, NJ), Masat; Linda (Walnut Creek, CA), Huang; Chao Bai (San Leandro, CA), Takeuchi; Toshihiko (Oakland, CA), Kantak; Seema (Pacifica, CA), Huang; Chin-Yi (Fremont, CA)
Assignee: Schering Corporation (Kenilworth, NJ)
Application Number:12/739,383
Patent Claims:see list of patent claims

Details for Patent 8,216,571

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 002 2004-02-26   Start Trial Schering Corporation (Kenilworth, NJ) 2027-10-22 RX Orphan search
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 001 2004-02-26   Start Trial Schering Corporation (Kenilworth, NJ) 2027-10-22 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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