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Last Updated: September 27, 2020

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Patent: 8,202,513

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Summary for Patent: 8,202,513
Title:Aryl potassium channel blockers and uses thereof
Abstract: The present invention relates to compounds useful in the modulation of potassium channel activity in cells, in particular the activity of Kv1.3 channels found in T cells. The invention also relates to the use of these compounds in the treatment or prevention of autoimmune and inflammatory diseases, including multiple sclerosis, pharmaceutical compositions containing these compounds and methods for their preparation.
Inventor(s): Flynn; Bernard Luke (Vermont, AU), Baell; Jonathan Bayldon (Ivanhoe, AU), Chaplin; Jason Hugh (DoubleView, AU), Gill; Gurmit Singh (Craigieburn, AU), Grobelny; Damian Wojciech (Watsonia, AU), Harvey; Andrew John (Goodwood, AU), Mould; Jorgen Alvar (Semaphore, AU), Paul; Dharam (Torrensville, AU)
Assignee: Bionomics Limited (Thebarton, South Australia, AU)
Application Number:12/681,763
Patent Claims:see list of patent claims

Details for Patent 8,202,513

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Bayer Healthcare Pharms BETASERON interferon beta-1b VIAL; SUBCUTANEOUS 103471 001 1993-07-23   Start Trial Bionomics Limited (Thebarton, South Australia, AU) 2027-10-04 RX Orphan search
Biogen AVONEX interferon beta-1a VIAL 103628 001 1996-05-17   Start Trial Bionomics Limited (Thebarton, South Australia, AU) 2027-10-04 RX search
Serono Inc REBIF interferon beta-1a SYRINGE 103780 001 2002-03-07   Start Trial Bionomics Limited (Thebarton, South Australia, AU) 2027-10-04 RX search
Serono Inc REBIF interferon beta-1a SYRINGE 103780 002 2002-03-07   Start Trial Bionomics Limited (Thebarton, South Australia, AU) 2027-10-04 RX search
Biogen Idec TYSABRI natalizumab VIAL; SINGLE-USE 125104 001 2004-11-23   Start Trial Bionomics Limited (Thebarton, South Australia, AU) 2027-10-04 RX search
Novartis Pharms EXTAVIA interferon beta-1b INJECTABLE; SUBCUTANEOUS 125290 001 2009-08-14   Start Trial Bionomics Limited (Thebarton, South Australia, AU) 2027-10-04 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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