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Last Updated: August 11, 2020

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Patent: 8,182,812

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Summary for Patent: 8,182,812
Title:Human monoclonal antibodies against CD25
Abstract: Isolated human monoclonal antibodies which bind to and inhibit human CD25, and related antibody-based compositions and molecules, are disclosed. The human antibodies can be produced by a hybridoma, a transfectoma or in a nonhuman transgenic animal, e.g., a transgenic mouse, capable of producing multiple isotypes of human monoclonal antibodies by undergoing V-D-J recombination and isotype switching. Also disclosed are pharmaceutical compositions comprising the human antibodies, nonhuman transgenic animals, hybridomas and transfectomas which produce the human antibodies, and therapeutic and diagnostic methods for using the human antibodies.
Inventor(s): Schuurman; Janine (Amsterdam, NL), Havenith; Catharina Emanuele Gerarda (Bodegraven, NL), Parren; Paul (Odijk, NL), Van De Winkel; Jan G. J. (Zeist, NL), Williams; Denise Leah (San Jose, CA), Petersen; Jorgen (Rungsted Kyst, DK), Baadsgaard; Ole (Malmo, SE)
Assignee: Genmab A/S (Copenhagen, DK)
Application Number:12/283,775
Patent Claims:see list of patent claims

Details for Patent 8,182,812

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Immunex ENBREL etanercept SYRINGE 103795 002 1998-11-02   Start Trial Genmab A/S (Copenhagen, DK) 2039-03-29 RX Orphan search
Immunex ENBREL etanercept VIAL; SUBCUTANEOUS 103795 001 1998-11-02   Start Trial Genmab A/S (Copenhagen, DK) 2039-03-29 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

International Patent Family for US Patent 8,182,812

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