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Last Updated: December 8, 2021

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Patent: 8,178,123

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Summary for Patent: 8,178,123
Title:Method for augmentation of intraepithelial and systemic exposure of therapeutic agents having substrate activity for cytochrome P450 enzymes and membrane efflux systems following vaginal and oral cavity administration
Abstract: A vaginal or buccal delivery of therapeutic agents having a substrate affinity for metabolic cytochrome P-450 enzymes and membrane efflux transporter systems. A method for augmentation of systemic exposure to the therapeutic agents having a substrate affinity for cytochrome P-450 enzymes and membrane efflux transporter systems, by delivering said agents to the systemic circulation through vaginal or buccal mucosa.
Inventor(s): Pauletti; Giovanni M. (Loveland, OH), Harrison; Donald C. (Cincinnati, OH), Desai; Kishorkumar J. (Westchester, OH)
Assignee: Femina Pharma Incorporated (Miami, FL)
Application Number:11/522,126
Patent Claims:see list of patent claims

Details for Patent 8,178,123

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Eli Lilly And Company HUMATROPE somatropin For Injection 019640 1987-06-23 ⤷  Free Forever Trial 2021-08-29
Eli Lilly And Company HUMATROPE somatropin For Injection 019640 1986-10-16 ⤷  Free Forever Trial 2021-08-29
Eli Lilly And Company HUMATROPE somatropin For Injection 019640 1999-02-04 ⤷  Free Forever Trial 2021-08-29
Emd Serono, Inc. SAIZEN somatropin For Injection 019764 1996-10-08 ⤷  Free Forever Trial 2021-08-29
Emd Serono, Inc. SAIZEN somatropin For Injection 019764 2000-08-29 ⤷  Free Forever Trial 2021-08-29
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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