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Last Updated: October 1, 2020

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Patent: 8,173,627

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Summary for Patent: 8,173,627
Title:Neuroprotective effect of solubilized UDCA in focal ischemic model
Abstract: The present disclosure provides compositions and methods for treating, ameliorating, or relieving at least one symptom associated with loss of blood flow to the brain including, without limitation, ischemic stroke. Compositions of the disclosure may comprise a bile acid compound and a carbohydrate, wherein both materials remain in solution for all pH values of the solution within a selected range of pH values. Symptoms may include infarct volume, functional recovery, apoptosis, and/or eNOS expression.
Inventor(s): Yoo; Seo Hong (Wyckoff, NJ)
Assignee:
Application Number:11/215,701
Patent Claims:see list of patent claims

Details for Patent 8,173,627

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Centocor Inc REOPRO abciximab INJECTABLE; INJECTION 103575 001 1994-12-22   Start Trial 2024-08-30 RX search
Genentech CATHFLO ACTIVASE alteplase VIAL 103172 003 1987-11-13   Start Trial 2024-08-30 RX search
Genentech ACTIVASE alteplase VIAL; SINGLE-USE 103172 002 1987-11-13   Start Trial 2024-08-30 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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Serving leading biopharmaceutical companies globally:

McKesson
AstraZeneca
Medtronic
Express Scripts
Colorcon
Moodys

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