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Last Updated: September 18, 2020

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Patent: 8,148,079

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Summary for Patent: 8,148,079
Title:Method of producing amplification product by PCR and usage thereof
Abstract: A method of producing a PCR amplification product is provided that suppresses an effect of precipitate, turbidity, or the like derived from a whole blood sample on a detection in the detection of an amplified nucleic acid by an optical unit. The amplification product complementary to a target nucleic acid in the whole blood sample is produced by PCR in a condition where a ratio of the whole blood sample in a PCR reaction solution is in the range of 0.1 to 0.9% by volume or 0.01 to 1.8 g/L in term of hemoglobin content. When the PCR is carried out with such conditions, even with an untreated whole blood sample, a monitoring of the amplification product by the optical unit can be done while suppressing the effect of the precipitate or the turbidity.
Inventor(s): Izumizawa; Yuji (Kyoto, JP), Majima; Satoshi (Kyoto, JP)
Assignee: ARKRAY, Inc. (Kyoto, JP)
Application Number:12/294,304
Patent Claims:see list of patent claims

Details for Patent 8,148,079

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Grifols Usa, Llc PLASBUMIN albumin (human) SOLUTION 101138 1 1994-09-26   Start Trial ARKRAY, Inc. (Kyoto, JP) 2026-08-09 search
Baxalta Us Inc. FLEXBUMIN albumin human INJECTION, SOLUTION 101452 1 2014-07-31   Start Trial ARKRAY, Inc. (Kyoto, JP) 2026-08-09 search
Csl Behring Ag ALBURX albumin (human) SOLUTION 102366 1 2009-01-06   Start Trial ARKRAY, Inc. (Kyoto, JP) 2026-08-09 search
Grifols Usa, Llc ALBUTEIN albumin (human) INJECTION, SOLUTION 102478 1 2019-12-15   Start Trial ARKRAY, Inc. (Kyoto, JP) 2026-08-09 search
Grifols Usa, Llc HUMAN ALBUMIN GRIFOLS albumin (human) SOLUTION 103352 1 2003-06-11   Start Trial ARKRAY, Inc. (Kyoto, JP) 2026-08-09 search
Csl Behring Llc ALBUMINAR-25 albumin (human) SOLUTION 103955 1 2009-01-06   Start Trial ARKRAY, Inc. (Kyoto, JP) 2026-08-09 search
Octapharma Usa Inc ALBUMIN (HUMAN) albumin human SOLUTION 125154 1 2006-10-17   Start Trial ARKRAY, Inc. (Kyoto, JP) 2026-08-09 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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