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Last Updated: September 24, 2020

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Patent: 8,142,794

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Summary for Patent: 8,142,794
Title:Hepatitis C virus vaccine
Abstract: The present invention features Ad6 vectors and a nucleic acid encoding a Met-NS3-NS4A-NS4B-NS5A-NS5B polypeptide containing an inactive NS5B RNA-dependent RNA polymerase region. The nucleic acid is particularly useful as a component of an adenovector or DNA plasmid vaccine providing a broad range of antigens for generating an HCV specific cell mediated immune (CMI) response against HCV.
Inventor(s): Emini; Emilio A. (Wayne, PA), Kaslow; David C. (Rancho Santa Fe, CA), Bett; Andrew J. (Lansdale, PA), Shiver; John W. (Chalfont, PA), Nicosia; Alfredo (Rome, IT), Lahm; Armin (Rome, IT), Luzzago; Alessandra (Rome, IT), Cortese; Riccardo (Rome, IT), Colloca; Stefano (Rome, IT)
Assignee: Merck Sharp & Dohme Corp. (Rahway, NJ)
Application Number:12/396,747
Patent Claims:see list of patent claims

Details for Patent 8,142,794

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04   Start Trial Merck Sharp & Dohme Corp. (Rahway, NJ) 2021-10-11 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04   Start Trial Merck Sharp & Dohme Corp. (Rahway, NJ) 2021-10-11 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04   Start Trial Merck Sharp & Dohme Corp. (Rahway, NJ) 2021-10-11 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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