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Last Updated: October 1, 2020

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Patent: 8,133,707

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Summary for Patent: 8,133,707
Title:Methods of preparing activated polymers having alpha nitrogen groups
Abstract: Methods for preparing substantially non-antigenic polymers having lone electron pair-containing moieties in high purity are disclosed. The polymers are useful as intermediates for synthesis of amine-based polymers and in the formation of activated polymers for conjugation with nucleophiles. Conjugates and methods of preparation and treatment with the conjugates are also disclosed. The resultant polymer-amines are of sufficient purity so that expensive and time consuming purification steps required for pharmaceutical grade polymers are avoided.
Inventor(s): Zhao; Hong (Edison, NJ), Wu; Dechun (Bridgewater, NJ)
Assignee: Enzon Pharmaceuticals, Inc. (Piscataway, NJ)
Application Number:11/333,072
Patent Claims:see list of patent claims

Details for Patent 8,133,707

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck ELSPAR asparaginase VIAL 101063 001 1978-01-10   Start Trial Enzon Pharmaceuticals, Inc. (Piscataway, NJ) 2039-02-26 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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