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Last Updated: September 28, 2020

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Patent: 8,114,969

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Summary for Patent: 8,114,969
Title:Immunotoxin derived from a recombinant human autoantibody and method of using thereof
Abstract: The invention is directed to an immunotoxin directed at fetal AchR, wherein the immunotoxin may comprises a human Fab fragment based on a human autoantibody or human combinatorial CDNA library and may be a pseudomonas exotoxin A-based single chain Fv IT (35-scFV-ETA). The invention is further directed to method of treating a patient with soft tissue tumor comprising the step of exposing the patient to the immunotoxin of the invention.
Inventor(s): Vincent; Angela (Wellington Square, GB), Marx; Alexander (Wurzburg, GB), Gattenlohner; Stefan (Wurzburg, GB)
Assignee: ISIS Innovation, Ltd. (Oxford, GB)
Application Number:10/950,677
Patent Claims:see list of patent claims

Details for Patent 8,114,969

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck ELSPAR asparaginase VIAL 101063 001 1978-01-10   Start Trial ISIS Innovation, Ltd. (Oxford, GB) 2023-10-01 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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