Make Better Decisions - Finding and Evaluating Generic and Branded Drug Market Entry Opportunities

Get the Book: Make Better Decisions

Finding and Evaluating Generic and Branded Drug Market Entry Opportunities

PDF eBook: Just $10 Get Print Book on Amazon

Serving hundreds of leading biopharmaceutical companies globally:

Moodys
Daiichi Sankyo
US Army
Cantor Fitzgerald
Citi
Covington

Generated: September 23, 2019

DrugPatentWatch Database Preview

Patent: 8,088,737

  Try a free trial


See Plans and Pricing

« Back to Dashboard

Summary for Patent: 8,088,737
Title:Compositions, methods and kits relating to Her-2 cleavage
Abstract: The present invention relates to compositions, methods and kits based on the ADAM-mediated cleavage of Her-2. The present invention also relates to treatments for cancer, and in particular, breast cancer, by modulating the ADAM-mediated cleavage of Her-2. Further, the invention relates to compositions, methods and kits based on the surprising synergistic effect between inhibition of Her-2 cleavage by an ADAM and certain cytostatic (e.g., Herceptin) and cytotoxic (e.g., Taxol) compounds in, among other things, inhibiting tumor cell proliferation and inducing cell death. Additionally, the invention relates to novel variants of ADAM15, designated ADAM15 variant 1 and ADAM15 variant 2, now identified and isolated.
Inventor(s): Friedman; Steven M. (West Chester, PA), Scherle; Peggy A. (Media, PA), Liu; Xiangdong (Metchuen, NJ), Burn; Timothy C. (Hockessin, DE), Huber; Reid (Wilmington, DE), Liu; Phillip C. C. (Wilmington, DE), Hollis; Gregory F. (Wilmington, DE), Vaddi; Krishna (Hockessin, DE), Fridman; Jordan S. (Newark, DE)
Assignee: Incyte Corporation (Wilmington, DE)
Application Number:10/817,718
Patent Claims:see list of patent claims

Details for Patent 8,088,737

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech HERCEPTIN trastuzumab VIAL; INTRAVENOUS 103792 001 1998-09-25 ➤ Sign Up Incyte Corporation (Wilmington, DE) 2023-05-22 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

Make Better Decisions: Try a trial or see plans & pricing

Serving hundreds of leading biopharmaceutical companies globally:

Teva
Medtronic
Merck
Queensland Health
Fuji
Daiichi Sankyo

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.