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Last Updated: September 19, 2020

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Patent: 8,084,426

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Summary for Patent: 8,084,426
Title:Pharmaceutical composition comprising FGF18 and IL-1 antagonist and method of use
Abstract: FGF18 is known to stimulate the proliferation of chondrocytes, bone, and nervous tissue, resulting in repair of diseased tissue. When an IL-1 antagonist is administered in addition to FGF18, the effects on the IL-1 mediated disease and also, the effect on cartilage, bone, and nervous cell proliferation, are found to be greater than administration of FGF18 or the IL-1 antagonist alone. The present invention encompasses a pharmaceutical composition that combines FGF18 with IL-1 antagonist and methods of treating IL-1 mediated disease using this pharmaceutical composition.
Inventor(s): Moore; Emma E. (Seattle, WA), Ellsworth; Jeff L. (Seattle, WA)
Assignee: ZymoGenetics, Inc. (Seattle, WA)
Application Number:12/784,377
Patent Claims:see list of patent claims

Details for Patent 8,084,426

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Biovitrum Ab KINERET anakinra VIAL; SUBCUTANEOUS 103950 001 2001-11-14   Start Trial ZymoGenetics, Inc. (Seattle, WA) 2024-07-06 RX search
Biovitrum Ab KINERET anakinra VIAL; SUBCUTANEOUS 103950 002 2001-11-14   Start Trial ZymoGenetics, Inc. (Seattle, WA) 2024-07-06 RX search
Biovitrum Ab KINERET anakinra VIAL; SUBCUTANEOUS 103950 003 2001-11-14   Start Trial ZymoGenetics, Inc. (Seattle, WA) 2024-07-06 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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