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Last Updated: December 1, 2021

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Patent: 8,062,897

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Summary for Patent: 8,062,897
Title:Diagnostic histopathology using multiplex gene expression FISH
Abstract: The present invention relates to a method for detecting one or more nascent RNAs in a tissue sample using FISH. In the method, a plurality of probes (8 to 82) may be used to detect a single species of nascent RNA. Further, a plurality of nascent RNA species may be detected simultaneously using between 8 and 82 probes for each nascent RNA. The invention comprises, in addition, methods of preparing a sample for nascent RNA detection by reducing autofluorescence of the tissue sample. These techniques may be synergistically combined to achieve significantly improved results.
Inventor(s): Capodieci; Paola (New York, NY), Donovan; Michael J. (Boston, MA)
Assignee: Aureon Laboratories, Inc. (Yonkers, NY)
Application Number:11/404,272
Patent Claims:see list of patent claims

Details for Patent 8,062,897

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 1986-06-04 ⤷  Try it Free 2023-07-21
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 ⤷  Try it Free 2023-07-21
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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