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Last Updated: September 24, 2020

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Patent: 8,062,663

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Summary for Patent: 8,062,663
Title:Methods and compostions for enhancing transdermal drug delivery
Abstract: Methods and compositions for enhancing transdermal delivery of a bioactive agent. The method contains the step of applying to a skin tissue an effective amount of a composition comprising: (a) a drug vehicle; (b) a bioactive agent encapsulated within the drug vehicle; (c) a plurality of proteolytic enzyme molecules conjugated onto the surface of the drug vehicle; and (d) a pharmaceutically acceptable carrier, for a period of time effective to deliver the bioactive agent across the skin tissue at a desired dosage.
Inventor(s): Wang; Yu-Jing (Taichung, TW), Wang; Yu-Chao (Taipei, TW), Wu; Yi-Ting (Taoyuan, TW), Tai; Lin-Ai (Hsin-Chu, TW), Lo; Leu-Wei (Taipei, TW), Yang; Chung-Shi (Taichung, TW)
Assignee: National Health Research Instittues (Miaoli County, TW)
Application Number:12/466,011
Patent Claims:see list of patent claims

Details for Patent 8,062,663

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Bausch And Lomb VITRASE hyaluronidase INJECTABLE;INJECTION 021640 001 2004-12-21   Start Trial National Health Research Instittues (Miaoli County, TW) 2028-05-23 RX search
Bausch And Lomb VITRASE hyaluronidase INJECTABLE;INJECTION 021640 002 2004-12-21   Start Trial National Health Research Instittues (Miaoli County, TW) 2028-05-23 RX search
Amphastar Pharm AMPHADASE hyaluronidase INJECTABLE;INJECTION 021665 001 2005-11-03   Start Trial National Health Research Instittues (Miaoli County, TW) 2028-05-23 RX search
Akorn Inc HYDASE hyaluronidase INJECTABLE;INJECTION 021716 001 2005-10-25   Start Trial National Health Research Instittues (Miaoli County, TW) 2028-05-23 DISCN search
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04   Start Trial National Health Research Instittues (Miaoli County, TW) 2028-05-23 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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