Patent: 8,062,663
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Summary for Patent: 8,062,663
Title: | Methods and compostions for enhancing transdermal drug delivery |
Abstract: | Methods and compositions for enhancing transdermal delivery of a bioactive agent. The method contains the step of applying to a skin tissue an effective amount of a composition comprising: (a) a drug vehicle; (b) a bioactive agent encapsulated within the drug vehicle; (c) a plurality of proteolytic enzyme molecules conjugated onto the surface of the drug vehicle; and (d) a pharmaceutically acceptable carrier, for a period of time effective to deliver the bioactive agent across the skin tissue at a desired dosage. |
Inventor(s): | Wang; Yu-Jing (Taichung, TW), Wang; Yu-Chao (Taipei, TW), Wu; Yi-Ting (Taoyuan, TW), Tai; Lin-Ai (Hsin-Chu, TW), Lo; Leu-Wei (Taipei, TW), Yang; Chung-Shi (Taichung, TW) |
Assignee: | National Health Research Instittues (Miaoli County, TW) |
Application Number: | 12/466,011 |
Patent Claims: | see list of patent claims |
Details for Patent 8,062,663
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Bausch & Lomb Incorporated | VITRASE | hyaluronidase | Injection | 021640 | 05/05/2004 | ⤷ Sign Up | 2028-05-23 |
Bausch & Lomb Incorporated | VITRASE | hyaluronidase | Injection | 021640 | 12/02/2004 | ⤷ Sign Up | 2028-05-23 |
Amphastar Pharmaceuticals, Inc. | AMPHADASE | hyaluronidase | Injection | 021665 | 10/26/2004 | ⤷ Sign Up | 2028-05-23 |
Akorn, Inc. | HYDASE | hyaluronidase | Injection | 021716 | 10/25/2005 | ⤷ Sign Up | 2028-05-23 |
Smith & Nephew, Inc. | SANTYL | collagenase | Ointment | 101995 | 06/04/1965 | ⤷ Sign Up | 2028-05-23 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |