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Last Updated: March 30, 2023

Patent: 8,062,663

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Summary for Patent: 8,062,663
Title:Methods and compostions for enhancing transdermal drug delivery
Abstract: Methods and compositions for enhancing transdermal delivery of a bioactive agent. The method contains the step of applying to a skin tissue an effective amount of a composition comprising: (a) a drug vehicle; (b) a bioactive agent encapsulated within the drug vehicle; (c) a plurality of proteolytic enzyme molecules conjugated onto the surface of the drug vehicle; and (d) a pharmaceutically acceptable carrier, for a period of time effective to deliver the bioactive agent across the skin tissue at a desired dosage.
Inventor(s): Wang; Yu-Jing (Taichung, TW), Wang; Yu-Chao (Taipei, TW), Wu; Yi-Ting (Taoyuan, TW), Tai; Lin-Ai (Hsin-Chu, TW), Lo; Leu-Wei (Taipei, TW), Yang; Chung-Shi (Taichung, TW)
Assignee: National Health Research Instittues (Miaoli County, TW)
Application Number:12/466,011
Patent Claims:see list of patent claims

Details for Patent 8,062,663

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Bausch & Lomb Incorporated VITRASE hyaluronidase Injection 021640 05/05/2004 ⤷  Sign Up 2028-05-23
Bausch & Lomb Incorporated VITRASE hyaluronidase Injection 021640 12/02/2004 ⤷  Sign Up 2028-05-23
Amphastar Pharmaceuticals, Inc. AMPHADASE hyaluronidase Injection 021665 10/26/2004 ⤷  Sign Up 2028-05-23
Akorn, Inc. HYDASE hyaluronidase Injection 021716 10/25/2005 ⤷  Sign Up 2028-05-23
Smith & Nephew, Inc. SANTYL collagenase Ointment 101995 06/04/1965 ⤷  Sign Up 2028-05-23
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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