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Last Updated: December 7, 2021

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Patent: 8,057,814

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Summary for Patent: 8,057,814
Title:Drug delivery from stents
Abstract: An intravascular stent has a coat comprising a crosslinked amphiphilic polymer and a sparingly water soluble matrix metalloproteinase inhibitor (MMPI). Preferably the polymer is formed from 2-methacryloyloxy-2\'-ethyltrimethylammonium phosphate inner salt, C.sub.4-18 alkyl methacrylate and reactive and/or crosslinking monomer and the MMPI is a hydroxamic acid, more preferably batimastat. Preclinical and clinical results are reported, showing good luminal areas and reduced intimal thickening.
Inventor(s): Lewis; Andrew L. (Surrey, GB), Stratford; Peter W. (Surrey, GB), Driver; Michael J. (Surrey, GB)
Assignee: Abbott Laboratories (Abbott Park, IL)
Application Number:12/773,674
Patent Claims:see list of patent claims

Details for Patent 8,057,814

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Smith & Nephew, Inc. SANTYL collagenase Ointment 101995 1965-06-04 ⤷  Try it Free 2021-01-11
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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