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Last Updated: September 30, 2020

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Patent: 8,057,814

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Summary for Patent: 8,057,814
Title:Drug delivery from stents
Abstract: An intravascular stent has a coat comprising a crosslinked amphiphilic polymer and a sparingly water soluble matrix metalloproteinase inhibitor (MMPI). Preferably the polymer is formed from 2-methacryloyloxy-2\'-ethyltrimethylammonium phosphate inner salt, C.sub.4-18 alkyl methacrylate and reactive and/or crosslinking monomer and the MMPI is a hydroxamic acid, more preferably batimastat. Preclinical and clinical results are reported, showing good luminal areas and reduced intimal thickening.
Inventor(s): Lewis; Andrew L. (Surrey, GB), Stratford; Peter W. (Surrey, GB), Driver; Michael J. (Surrey, GB)
Assignee: Abbott Laboratories (Abbott Park, IL)
Application Number:12/773,674
Patent Claims:see list of patent claims

Details for Patent 8,057,814

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04   Start Trial Abbott Laboratories (Abbott Park, IL) 2021-01-11 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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