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Generated: July 21, 2019

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Patent: 8,012,480

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Summary for Patent: 8,012,480
Title:Detection of proteins from circulating neoplastic cells
Abstract: The protein EGFR, ERCC1, RRM1, thymidylate synthase, or beta-tubulin from cancer cells is detected in a blood sample by enriching the cancer cells from the blood sample followed by performing on the enriched cancer cells an immunoassay capable of detecting the proteins mentioned above. Cancer patients overexpressing EGFR are treated with an anti-EGFR agent, for example cetuximab, panitumumab, erlotinib or gefitinib.
Inventor(s): Lorence; Robert M. (Bethesda, MD)
Assignee: Wellstat Biologics Corporation (Gaithersburg, MD)
Application Number:12/297,420
Patent Claims:see list of patent claims

Details for Patent 8,012,480

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source
Amgen VECTIBIX panitumumab INJECTABLE; IV (INFUSION) 125147 003 2006-09-27 ➤ Sign Up Wellstat Biologics Corporation (Gaithersburg, MD) ➤ Sign Up RX search
Amgen VECTIBIX panitumumab INJECTABLE; IV (INFUSION) 125147 002 2006-09-27 ➤ Sign Up Wellstat Biologics Corporation (Gaithersburg, MD) ➤ Sign Up RX search
Amgen VECTIBIX panitumumab INJECTABLE; IV (INFUSION) 125147 001 2006-09-27 ➤ Sign Up Wellstat Biologics Corporation (Gaithersburg, MD) ➤ Sign Up RX search
Imclone ERBITUX cetuximab VIAL; INTRAVENOUS 125084 001 2004-06-18 ➤ Sign Up Wellstat Biologics Corporation (Gaithersburg, MD) ➤ Sign Up RX Orphan search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source

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International Patent Family for US Patent 8,012,480

Country Patent Number Publication Date
World Intellectual Property Organization (WIPO) 2007121465 Jun 19, 2008
World Intellectual Property Organization (WIPO) 2007121465 Oct 25, 2007
World Intellectual Property Organization (WIPO) 2007121465 Sep 12, 2008
United States of America 2009098138 Apr 16, 2009
Mexico 2008013332 Nov 10, 2008
Japan 2009534667 Sep 24, 2009
Country Patent Number Publication Date

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