Nucleic acids encoding chimera botulinum toxin type E
The present invention relates to a toxin comprising a modified light chain of a botulinum toxin type E, wherein the modified light chain comprises amino acid sequence PFVNKQFN (SEQ ID NO: 120) at the N-terminus, and amino acid sequence xExxxLL (SEQ ID NO: 112) at the C-terminus, wherein x is any amino acid.
Fernandez-Salas; Ester (Fullerton, CA), Steward; Lance E. (Irvine, CA), Herrington; Todd (Brookline, MA), Aoki; K. Roger (Coto de Caza, CA)
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