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Last Updated: November 29, 2021

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Patent: 8,008,447

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Summary for Patent: 8,008,447
Title:Crystallization of antibody or fragment thereof
Abstract: The present disclosure concerns methods of crystallization and/or concentration of antibody or antibody fragments. The methods comprise contacting an antibody or antibody fragment with a solution comprising a salt of a divalent cation. Crystals and/or protein gels of antibody or antibody fragments are useful in compositions and formulations.
Inventor(s): Hagewiesche; Annette Marie Clasen (Carlsbad, CA), Fukami; Julie (Woodside, CA), Cromwell; Mary E. M. (Redwood City, CA), Dinges; Rachel Bulotsky (San Mateo, CA)
Assignee: Genentech, Inc. (South San Francisco, CA)
Application Number:11/572,369
Patent Claims:see list of patent claims

Details for Patent 8,008,447

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Genentech, Inc. AVASTIN bevacizumab Injection 125085 2004-02-26 ⤷  Try it Free 2024-07-23
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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Serving leading biopharmaceutical companies globally:

Harvard Business School
Johnson and Johnson
Boehringer Ingelheim

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