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Last Updated: February 26, 2020

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Patent: 8,008,447

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Summary for Patent: 8,008,447
Title:Crystallization of antibody or fragment thereof
Abstract: The present disclosure concerns methods of crystallization and/or concentration of antibody or antibody fragments. The methods comprise contacting an antibody or antibody fragment with a solution comprising a salt of a divalent cation. Crystals and/or protein gels of antibody or antibody fragments are useful in compositions and formulations.
Inventor(s): Hagewiesche; Annette Marie Clasen (Carlsbad, CA), Fukami; Julie (Woodside, CA), Cromwell; Mary E. M. (Redwood City, CA), Dinges; Rachel Bulotsky (San Mateo, CA)
Assignee: Genentech, Inc. (South San Francisco, CA)
Application Number:11/572,369
Patent Claims:see list of patent claims

Details for Patent 8,008,447

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 001 2004-02-26   Start Trial Genentech, Inc. (South San Francisco, CA) 2024-07-23 RX Orphan search
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 002 2004-02-26   Start Trial Genentech, Inc. (South San Francisco, CA) 2024-07-23 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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