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Last Updated: December 8, 2021

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Patent: 8,003,659

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Summary for Patent: 8,003,659
Title:Macrocyclic serine protease inhibitors
Abstract: Provided herein are macrocyclic serine protease inhibitor compounds, for example, of Formula I, pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host in need thereof. ##STR00001##
Inventor(s): Parsy; Christophe Claude (Jacou, FR), Alexandre; Francois-Rene (Montpellier, FR), Surleraux; Dominique (Wauthier-Braine, BE), Derock; Michel (Montpellier, FR), Leroy; Frederic (Jonquieres, FR)
Assignee: Indenix Pharmaceuticals, Inc. (Cambridge, MA)
Application Number:12/365,127
Patent Claims:see list of patent claims

Details for Patent 8,003,659

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Biogen Inc. AVONEX interferon beta-1a For Injection 103628 1996-05-17 ⤷  Free Forever Trial 2028-02-04
Biogen Inc. AVONEX interferon beta-1a Injection 103628 2003-05-28 ⤷  Free Forever Trial 2028-02-04
Biogen Inc. AVONEX interferon beta-1a Injection 103628 2012-02-27 ⤷  Free Forever Trial 2028-02-04
Kadmon Pharmaceuticals Llc INFERGEN interferon alfacon-1 Injection 103663 1997-10-06 ⤷  Free Forever Trial 2028-02-04
Emd Serono, Inc. REBIF interferon beta-1a Injection 103780 2002-03-07 ⤷  Free Forever Trial 2028-02-04
Emd Serono, Inc. REBIF interferon beta-1a Injection 103780 2004-12-17 ⤷  Free Forever Trial 2028-02-04
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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