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Last Updated: September 24, 2020

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Patent: 8,003,382

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Summary for Patent: 8,003,382
Title:Nucleic acid molecules encoding a house dust mite allergen Der f VII, and antigenic peptides thereof
Abstract: Isolated nucleic acids encoding allergens of the species Dermatophagoides pteronyssinus and Dermatophagoides farinae, Der p VII and Der f VII, respectively, are disclosed. A cDNA encoding a peptide having a Der p VII activity and a predicted molecular weight of about 22, 177 daltons is described. A cDNA encoding a peptide having Der f VII activity is also described. The nucleic acids of the invention can be used as probes to detect the presence of Der p VII or Der f VII nucleic acid in a sample or for the recombinant production of peptides having a Der p VII or Der f VII activity. Peptides having a Der p VII or Der f VII activity can be used in compositions suitable for pharmaceutical administration or methods of diagnosing sensitivity to house dust mite allergens.
Inventor(s): Thomas; Wayne R. (Nedlands, AU), Chua; Kaw-Yan (Nollamara, AU)
Assignee: Merck Patent GmbH (Darmstadt, DE)
Application Number:11/084,057
Patent Claims:see list of patent claims

Details for Patent 8,003,382

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Greer Laboratories, Inc. STANDARDIZED MITE DERMATOPHAGOIDES FARINAE dermatophagoides farinae CONCENTRATE 101834 1 2010-02-03   Start Trial Merck Patent GmbH (Darmstadt, DE) 2013-03-12 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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