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Last Updated: September 30, 2020

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Patent: 8,003,096

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Summary for Patent: 8,003,096
Title:Means and methods for the recruitment and identification of stem cells
Abstract: Described are methods of modulating stem/progenitor cell recruitment involving molecules that agonize the formation of plasmin stimulating the recruitment of stem/progenitor cells, including hematopoietic and endothelial precursor cells. Conversely, antagonists of plasmin can inhibit recruitment of the stem cells. In addition, the identification of the uPA receptor (uPAR) as a retention signal for stem cells in their niche suggests a novel method for increased engraftment and isolation of multipotent stem cells.
Inventor(s): Carmeliet; Peter (Blanden, BE), Tjwa; Marc (Leuven, BE)
Assignee: Vlaams Interuniversitair Instituut voor Biotechnologie VZW (Zwijnaarde, BE) Life Sciences Research Partners VZW (Leuven, BE)
Application Number:11/390,931
Patent Claims:see list of patent claims

Details for Patent 8,003,096

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Microbix Biosystems KINLYTIC urokinase INJECTABLE;INJECTION 021846 001 1978-01-16   Start Trial Vlaams Interuniversitair Instituut voor Biotechnologie VZW (Zwijnaarde, BE) Life Sciences Research Partners VZW (Leuven, BE) 2023-10-03 DISCN search
Microbix Biosystems KINLYTIC urokinase INJECTABLE;INJECTION 021846 002 1978-01-16   Start Trial Vlaams Interuniversitair Instituut voor Biotechnologie VZW (Zwijnaarde, BE) Life Sciences Research Partners VZW (Leuven, BE) 2023-10-03 DISCN search
Microbix Biosystems KINLYTIC urokinase INJECTABLE;INJECTION 021846 003 1978-01-16   Start Trial Vlaams Interuniversitair Instituut voor Biotechnologie VZW (Zwijnaarde, BE) Life Sciences Research Partners VZW (Leuven, BE) 2023-10-03 DISCN search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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