Upgrade for Complete Access See Plans and Pricing

Serving leading biopharmaceutical companies globally:

Express Scripts

Last Updated: December 5, 2021

DrugPatentWatch Database Preview

Patent: 7,993,638

➤ Subscribe for complete access

« Back to Dashboard

Summary for Patent: 7,993,638
Title:Cancer treatment combining lymphodepleting agent with CTLs and cytokines
Abstract: In a cancer treatment combining cell therapy with chemotherapy, autologous CD8.sup.+ T cells are obtained from a patient, activated ex vivo by contacting them with xenogenic antigen presenting cells loaded with selected peptide antigen, thereby generating antigen-specific activated cytotoxic T lymphocytes. Such activated CTLs are administered to the patient in conjunction with a lymphodepletion and CTL maintenance regimen comprising a non-myeloblative but lymphdepleting agent, such as cladribine or denileukin diftitox, and interleukin-2 and interferon-.alpha.-2b stimulatory cytokines.
Inventor(s): Cai; Zeling (San Diego, CA), Moriarty; Ann (Poway, CA), Peterson; Per A. (Rancho Santa Fe, CA), Richards; Jon M. (Glenview, IL)
Assignee: Janssen Pharmaceutica NV (BE)
Application Number:12/281,197
Patent Claims:see list of patent claims

Details for Patent 7,993,638

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Eisai, Incorporated ONTAK denileukin diftitox Injection 103767 1999-02-05 ⤷  Try it Free 2026-03-01
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

Make Better Decisions: Try a trial or see plans & pricing

Serving leading biopharmaceutical companies globally:

Boehringer Ingelheim
Express Scripts

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.