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Last Updated: February 28, 2020

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Patent: 7,985,549

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Summary for Patent: 7,985,549
Title:Method for predicting responsiveness to TNF.alpha. blocking agents
Abstract: The invention provides an in vitro method for predicting whether a patient would be responsive to a treatment with a TNF.alpha. blocking agent, which method comprises determining the expression level of eight genes in a biological sample of said patient, wherein said genes are EPS15, HLA-DPB1, AKAP9, RASGRP3, MTCBP-1, PTNP12, MRPL22 and RPS28. The invention further provides a DNA chip for performing such method.
Inventor(s): Salier; Jean-Philippe (Les Authieux-Ratieville, FR), Daveau; Maryvonne (Mont-Saint-Aignan, FR), Gauthier-Jauneau; Anne-Christine (Pont de I\'Arche, FR), Vittecoq; Olivier (Saint Ouen de Thouberville, FR), Loet; Xavier Le (Rouen, FR), Daragon; Alain (Rouen, FR), Mejjad; Othmane (Houppeville, FR), Lequerre; Thierry (MontMain, FR)
Assignee: INSERM (Institut National de la Sante et de la Recherche Medicale) (Paris cedex, FR)
Application Number:12/300,847
Patent Claims:see list of patent claims

Details for Patent 7,985,549

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Centocor Inc REMICADE infliximab VIAL 103772 001 1998-08-24   Start Trial INSERM (Institut National de la Sante et de la Recherche Medicale) (Paris cedex, FR) 2026-05-16 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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