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Last Updated: November 29, 2021

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Patent: 7,985,549

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Summary for Patent: 7,985,549
Title:Method for predicting responsiveness to TNF.alpha. blocking agents
Abstract: The invention provides an in vitro method for predicting whether a patient would be responsive to a treatment with a TNF.alpha. blocking agent, which method comprises determining the expression level of eight genes in a biological sample of said patient, wherein said genes are EPS15, HLA-DPB1, AKAP9, RASGRP3, MTCBP-1, PTNP12, MRPL22 and RPS28. The invention further provides a DNA chip for performing such method.
Inventor(s): Salier; Jean-Philippe (Les Authieux-Ratieville, FR), Daveau; Maryvonne (Mont-Saint-Aignan, FR), Gauthier-Jauneau; Anne-Christine (Pont de I\'Arche, FR), Vittecoq; Olivier (Saint Ouen de Thouberville, FR), Loet; Xavier Le (Rouen, FR), Daragon; Alain (Rouen, FR), Mejjad; Othmane (Houppeville, FR), Lequerre; Thierry (MontMain, FR)
Assignee: INSERM (Institut National de la Sante et de la Recherche Medicale) (Paris cedex, FR)
Application Number:12/300,847
Patent Claims:see list of patent claims

Details for Patent 7,985,549

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Janssen Biotech, Inc. REMICADE infliximab For Injection 103772 1998-08-24 ⤷  Try it Free 2026-05-16
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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