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Last Updated: December 7, 2021

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Patent: 7,964,219

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Summary for Patent: 7,964,219
Title:Pharmaceutical compositions for controlled release delivery of biologically active compounds
Abstract: The present invention provides compositions and methods for the controlled release delivery of one or more biologically active compounds to a subject. Specifically, the invention provides for a pharmaceutical composition for the controlled release delivery of biologically active compounds to a subject comprising: a) a complex of a biologically active compound having at least one basic functional group and a polyanion derived from hexahydroxycyclohexane having at least two negatively charged functional groups; and b) a pharmaceutically acceptable carrier comprising a biodegradable, water-insoluble polymer. By complexing a biologically active compound with a polyanion, the tight, stable complex may be incorporated into a long-acting dosage system having a more desired drug release curve over time than that is found in the prior art. The invention also provides the methods of making such compositions and the methods of use thereof.
Inventor(s): Li; Yuhua (Newark, DE), Chien; Benjamin (Newark, DE)
Assignee: QPS, LLC (Newark, DE)
Application Number:11/201,932
Patent Claims:see list of patent claims

Details for Patent 7,964,219

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Microbix Biosystems Inc. KINLYTIC urokinase For Injection 021846 1978-01-16 ⤷  Try it Free 2024-08-12
Nps Pharmaceuticals, Inc. NATPARA parathyroid hormone For Injection 125511 2015-01-23 ⤷  Try it Free 2024-08-12
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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