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Generated: September 22, 2019

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Patent: 7,939,468

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Summary for Patent: 7,939,468
Title:Methods of identifying compounds that target tRNA splicing endonuclease and uses of said compounds as anti-proliferative agents
Abstract: The present invention relates to a method for screening and identifying compounds that modulate the activity tRNA splicing endonuclease. In particular, the invention provides assays for the identification of compounds that inhibit animalia tRNA splicing endonuclease. The methods of the present invention provide a simple, sensitive assay for high-throughput screening of libraries of compounds to identify pharmaceutical leads useful for treating and/or preventing cancer.
Inventor(s): Trotta; Christopher R. (Somerset, NJ)
Assignee: PTC Therapeutics, Inc. (South Plainfield, NJ)
Application Number:12/756,786
Patent Claims:see list of patent claims

Details for Patent 7,939,468

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04   Try a Free Trial PTC Therapeutics, Inc. (South Plainfield, NJ) 2023-03-27 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04   Try a Free Trial PTC Therapeutics, Inc. (South Plainfield, NJ) 2023-03-27 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04   Try a Free Trial PTC Therapeutics, Inc. (South Plainfield, NJ) 2023-03-27 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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