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Last Updated: January 19, 2021

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Patent: 7,923,218

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Summary for Patent: 7,923,218
Title:Modulation of the integrin linked kinase signaling pathway to promote cardiac cell proliferation and self-renewal
Abstract: Modulation of the integrin-linked kinase (ILK) signaling pathway is used to enhance the remodeling process relevant to a wide range of cardiac diseases. More specifically, a process to instigate beneficial human cardiac hypertrophy or for post myocardial infarction (MI) remodeling comprising illiciting an overexpression of ILK, is described. The ILK signaling pathway is also used as a means for cardiac stem cell proliferation and self-renewal.
Inventor(s): Coles; John G. (Toronto, CA), Hannigan; Gregory (Toronto, CA), Lu; Huanzhang (Toronto, CA)
Assignee: Coles; John G. (Toronto, Ontario, CA)
Application Number:11/915,687
Patent Claims:see list of patent claims

Details for Patent 7,923,218

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04   Start Trial Coles; John G. (Toronto, Ontario, CA) 2039-03-29 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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